Recombinant Human MAPK12/p38 gamma, Active CRP103B from Cell Sciences

Description

MAPK12 is a member of the p38 MAPK family which is activated in response to stress. MAPK12 gene was mapped to 22q13.3 and functions as a signal transducer during differentiation of myoblasts to myotubes. Enforced localization of MAPK12 in the nucleus or cytoplasm markedly attenuates the ability of the kinase to induce cell cycle arrest in fibroblasts. MAPK12 increases basal glucose uptake and decreases DNP- and contraction-stimulated glucose uptake, partially by affecting levels of glucose transporter expression in skeletal muscle

Product Specs
ItemRecombinant Human MAPK12/p38 gamma, Active
CompanyCell Sciences
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberCRP103B
SpeciesHuman
Quantity10 µg
Source/Expression SystemSf9 cells
Activity> 200 nmol/min/mg:, by Kinase Specific Activity: nmol phosphate incorporated into the PKB-sub peptide (CKRPRAASFAE) per minute per mg protein at 30ºC for 15 minutes using a final concentration of 50 µM ATP (0.83 µCi/assay)
Molecule NameMAPK12
Concentration0.1 mg/ml
Format50 mM Tris-HCl, 150 mM NaCl, 10 mM glutathoine, 0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF, 25% Glycerol, pH 7.5
Purity> 90%, by SDS-PAGE (Coomassie)
TypeRecombinant Proteins
Molecular Weight~71 kDa
NCBI Full Gene Namemitogen-activated protein kinase 12
NCBI Gene AliasesP38GAMMA, ERK3, ERK6, PRKM12, ERK-6, MAPK 12, SAPK-3, SAPK3